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<i>Wikstroemia chamaedaphne<_i> Meisn.

" in MedChemExpress (MCE) Product Catalog:

2252

Inhibitors & Agonists

8

Screening Libraries

139

Fluorescent Dye

77

Biochemical Assay Reagents

235

Peptides

55

MCE Kits

31

Inhibitory Antibodies

390

Natural
Products

352

Recombinant Proteins

71

Isotope-Labeled Compounds

135

Antibodies

36

Click Chemistry

102

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147985
    hCA I-IN-1

    		Carbonic Anhydrase Cancer
    hCA I-IN-1 (Compound 6q) is a human carbonic anhydrase I (hCA I) inhibitor with Ki values of 38.3, 716.4, 940.1 and 192.8 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .
    hCA I-IN-1
  • HY-147986
    hCA I-IN-2

    		Carbonic Anhydrase Cancer
    hCA I-IN-2 (Compound 6d) is a selective human carbonic anhydrase I (hCA I) inhibitor with Ki values of 18.8, 375.1, 1721 and 283.9 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .
    hCA I-IN-2
  • HY-156969
    Topoisomerase I inhibitor 11

    		Topoisomerase Btk Cancer
    Topoisomerase I inhibitor 11 is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 11 can bind to BTK .
    Topoisomerase I inhibitor 11
  • HY-162091
    Topoisomerase I inhibitor 13

    		Topoisomerase Cancer
    Topoisomerase I inhibitor 13 (Compound G11) is a Topo I inhibitor that inhibits cancer cell proliferation. Topoisomerase I inhibitor 13 significantly inhibits tumor growth in vivo .
    Topoisomerase I inhibitor 13
  • HY-122949
    Momordicine I

    		DGK Metabolic Disease
    Momordicine I, a triterpenoid compound extracted from momordica charantia L. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ .
    Momordicine I
  • HY-N12370
    Tenaxin I

    		Others Others
    Tenaxin I is a component extracted from Radix Scutellariae with neuraminidase inhibitory activity .
    Tenaxin I
  • HY-146437
    Topoisomerase I inhibitor 6

    		Topoisomerase Cancer
    Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases .
    Topoisomerase I inhibitor 6
  • HY-P1032F
    Biotinyl-Angiotensin I (human, mouse, rat)

    		Endogenous Metabolite Endocrinology
    Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .
    Biotinyl-Angiotensin I (human, mouse, rat)
  • HY-149002
    Topoisomerase I/II inhibitor 4

    		Topoisomerase Apoptosis Cancer
    Topoisomerase I/II inhibitor 4 (compound F16) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 4 inhibits cell proliferation, invasion and migration and induces apoptosis. Topoisomerase I/II inhibitor 4 can be used for liver cancer research .
    Topoisomerase I/II inhibitor 4
  • HY-146497
    Topoisomerase I inhibitor 7

    		Topoisomerase Cancer
    Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones .
    Topoisomerase I inhibitor 7
  • HY-150685
    Topo I/COX-2-IN-1

    		Topoisomerase Prostaglandin Receptor Apoptosis Inflammation/Immunology Cancer
    Topo I/COX-2-IN-1 (1H-30) is a potential Topo I/COX-2 inhibitor. Topo I/COX-2-IN-1 inhibits COX-2 and Topo I with the IC50 value of 0.24 μM and 4.42 μM, respectively. Topo I/COX-2-IN-1 can induce apoptosis and inhibit migration of cancer cells, has anti-cancer activity .
    Topo I/COX-2-IN-1
  • HY-153340
    I-152

    		Keap1-Nrf2 Metabolic Disease
    I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties .
    I-152
  • HY-E70040
    Endoglycoceramidase I (EGCase I)

    		Endogenous Metabolite Metabolic Disease
    Endoglycoceramidase I (EGCase I) is a glycosidase, is often used in biochemical studies. Endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of GSLs to the primary hydroxyl group of several 1-alkanols .
    Endoglycoceramidase I (EGCase I)
  • HY-143265
    Topoisomerase I inhibitor 2

    		Topoisomerase Apoptosis Caspase Cancer
    Topoisomerase I inhibitor 2 (ZML-8) is a highly selective inhibitor of DNA topoisomerase I (Top1). Topoisomerase I inhibitor 2 inhibits Top1 activity and results DNA damage. Topoisomerase I inhibitor 2 blocks G2/M phase and induces apoptosis, exhibits anti-tumor effect .
    Topoisomerase I inhibitor 2
  • HY-P5798
    Fasciculin-I

    FAS-I

    		 Cholinesterase (ChE) Neurological Disease
    Fasciculin-I is isolated from the mambas venom. Fasciculin-I exerts its toxic effects by inhibiting acetylcholinesterase (AChE). Fasciculin-I blocks α-neurotoxins of nicotinic acetylcholine receptors and cardiac toxins that interact with cell membranes .
    Fasciculin-I
  • HY-P2774
    Glyoxalase I

    Glo-I

    		 Others Others
    Glyoxalase I (Glo-I) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Glyoxalase I
  • HY-131577A
    Neutral protease I

    Dispase I

    		 Others Others
    Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .
    Neutral protease I
  • HY-P5179
    Huwentoxin I

    HWTX-I

    		 Calcium Channel Sodium Channel Neurological Disease
    Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively .
    Huwentoxin I
  • HY-NP072
    Maackia Amurensis Lectin I

    MAL I

    		 Fluorescent Dye Others
    Maackia Amurensis Lectin I (MAL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) is a biological material or organic compound that can be used in life science research .
    Maackia Amurensis Lectin I
  • HY-NP079
    Ricinus Communis Agglutinin I

    RCA I

    		 Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I
  • HY-NP090
    Ulex Europaeus Agglutinin I

    UEA I

    		 Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I
  • HY-N12073
    Monofucosyllacto-N-hexaose I

    MFLNH I

    		 Others Others
    Monofucosyllacto-N-hexaose I (MFLNH I) is a composition of human milk oligosaccharide .
    Monofucosyllacto-N-hexaose I
  • HY-N2013R
    Aristolactam I (Standard)

    		Caspase Apoptosis Inflammation/Immunology
    Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway .
    Aristolactam I (Standard)
  • HY-136538
    LQZ-7I

    		Survivin Cancer
    LQZ-7I is a survivin-targeting inhibitor. LQZ-7I inhibits survivin dimerization. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors .
    LQZ-7I
  • HY-P3055
    Dendrotoxin-I

    DTX-I

    		 Potassium Channel Neurological Disease Cancer
    Dendrotoxin-I (DTX-I) is a potent K + channels blocker with IC50s of 0.13-50 nM for voltage-gated potassium channel subunits KV1.1, KV1.2 and KV1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .
    Dendrotoxin-I
  • HY-N11172
    Schibitubin I

    		Others Neurological Disease
    Schibitubin I is a lignin. Schibitubin I has neuroprotective activity. Schibitubin I can be isolated from the fruits of Schisandra bicolor var. tuberculata .
    Schibitubin I
  • HY-E70280
    Recombinant endoglycoceramidase I

    rEGCase I

    		 Biochemical Assay Reagents Metabolic Disease
    Recombinant endoglycoceramidase I (rEGCase I) is a glycosidase that catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides. Recombinant endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of glycosphingolipids (GSLs) to the primary hydroxyl group of several 1-alkanols .
    Recombinant endoglycoceramidase I
  • HY-N12727
    Okaramine I

    		Bacterial Infection
    Okaramine I is an Escherichia coli glycosyltransferase (MurG) inhibitor. Okaramine I can be used as an antibacterial agent. Okaramine I can be found in Aspergillus aculeatus .
    Okaramine I
  • HY-NP068
    Griffonia (Bandeiraea) Simplicifolia Lectin I

    GSL I

    		 Fluorescent Dye Others
    Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a biological material or organic compound that can be used in life science research .
    Griffonia (Bandeiraea) Simplicifolia Lectin I
  • HY-N12316
    Goshuyuamide I

    		Others Others
    Goshuyuamide-I (compound 4) is a kind of alkaloid. Goshuyuamide-I can be isolated from the fruits of Euodia rutaecarpa. Goshuyuamide-I can be used in the research of analgesics .
    Goshuyuamide I
  • HY-121934
    BH3I-2'

    		Others Cancer
    BH3I-2' is the BH3I-2 analogue. BH3I-2 is a Bcl-2 family inhibitor. BH3I-2' can be used for various studies .
    BH3I-2'
  • HY-107301
    Dehydrosoyasaponin I

    Soyasaponin Be; DHS-I

    		 Potassium Channel Neurological Disease
    Dehydrosoyasaponin I (Soyasaponin Be;DHS-I), a triterpene glycoside, is a potent and reversible calcium-activated potassium (maxi-K) channels activator .
    Dehydrosoyasaponin I
  • HY-P1768
    Urechistachykinin I

    Uru-TK I

    		 Bacterial Infection
    Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .
    Urechistachykinin I
  • HY-N0407R
    Picroside I (Standard)

    		STAT Inflammation/Immunology
    Picroside I (Standard) is the analytical standard of Picroside I. This product is intended for research and analytical applications. Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .
    Picroside I (Standard)
  • HY-NP0137
    Maackia Amurensis Lectin I (Fluorescein)

    MAL I (Fluorescein)

    		 Fluorescent Dye Others
    Maackia Amurensis Lectin I (MAL I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) Fluorescein is a biological material or organic compound that can be used in life science research .
    Maackia Amurensis Lectin I (Fluorescein)
  • HY-NP0141
    Ricinus Communis Agglutinin I (Fluorescein)

    RCA I (Fluorescein)

    		 Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Fluorescein is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I (Fluorescein)
  • HY-NP0145
    Ulex Europaeus Agglutinin I (Fluorescein)

    UEA I (Fluorescein)

    		 Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I (Fluorescein)
  • HY-NP0157
    Ricinus Communis Agglutinin I (Rhodamine)

    RCA I (Rhodamine)

    		 Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Rhodamine is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I (Rhodamine)
  • HY-NP0158
    Ulex Europaeus Agglutinin I (Rhodamine)

    UEA I (Rhodamine)

    		 Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I (Rhodamine)
  • HY-NP0168
    Ulex Europaeus Agglutinin I (Agarose)

    UEA I (Agarose)

    		 Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Agarose is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I (Agarose)
  • HY-NP0172
    Ricinus Communis Agglutinin I (Agarose)

    RCA I (Agarose)

    		 Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Agarose is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I (Agarose)
  • HY-NP0186
    Ricinus Communis Agglutinin I (Biotinylated)

    RCA I (Biotinylated)

    		 Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Biotinylated is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I (Biotinylated)
  • HY-NP0190
    Ulex Europaeus Agglutinin I (Biotinylated)

    UEA I (Biotinylated)

    		 Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Biotinylated is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I (Biotinylated)
  • HY-157034
    LU-002i

    		Proteasome Others
    LU-002i is a subunit-selective human proteasome β2c and β2i inhibitor with an IC50 value of 220 nM for β2i .
    LU-002i
  • HY-N2013
    Aristolactam I
    1 Publications Verification

    Aristololactam; Aristolactam

    		 Caspase Apoptosis Inflammation/Immunology
    Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway .
    Aristolactam I
  • HY-N1628
    1β-Hydroxybaccatin I

    1-Hydroxybaccatin I

    		 Others Others
    1β-Hydroxybaccatin I (1-Hydroxybaccatin I) can be extracted from Taxus wallichiana .
    1β-Hydroxybaccatin I
  • HY-N11430
    F1839-I

    		HIV Infection
    F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC50 value of 15.6 μM .
    F1839-I
  • HY-N10076
    Ganomycin I

    		HMG-CoA Reductase (HMGCR) Glucosidase HIV Protease Infection Metabolic Disease
    Ganomycin I is a dual inhibitor of α-Glucosidase and HMG-CoA reductase. Ganomycin I can also inhibits HIV protease. Ganomycin I exhibits anti-diabetic and anti-osteoclastogenesis effects .
    Ganomycin I
  • HY-117793
    I-191

    		Protease Activated Receptor (PAR) Cancer
    I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist .
    I-191
  • HY-153365
    I-138

    		Deubiquitinase Cancer
    I-138 is an orally active, reversible inhibitor of USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM), structurally related to ML323 (HY-17543). I-138 induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells .
    I-138

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